Cannabis History Timeline

Timeline of some of the major scientific milestones and influences on/in the cannabis, nano~technology and synthetic~biology industries/space over the past 215 years:

Year	Subject	Discovery/Milestone
1805	Morphine	Isolated from the poppy straw
1838	William O’Shaughessy	Introduced cannabis into the Western pharmacopoeia
1851	Marijuana	Is listed in the U.S Pharmacopoeia
1899	Aspirin	Synthesized and manufactured
1906	Pure Food Drug Act	Passed restricted labeling of cannabis as a poison
1920	Prohibition	Nationwide constitutional ban on alcohol enacted
1928	Penicillin	Discovered
1930	Anslinger	Harry J. appointed founding commissioner Fed. Bureau of Narcotics
1930	Vanilla	Extract synthesized and commercially available
1933	Vitamin C	(Ascorbic Acid) chemically produced
1936	Reefer Madness	Film released to HS students – harms of marijuana addiction
1937	Marihuana Tax	Act passed which imposed a tax on the sale of cannabis
1938	Food, Drug, Cosmetic Act	Legally mandated quality standards for drug claims
1957	Penicillin	Synthesized
1960	Counterculture decade	The use and panic over pot.
1964	Prof. Raphael Mechoulam	(Israel) Isolates and synthesizes THC
1966	Mahmoud A ELSohly	CBG, CBC, CBD, CBL, CBE, CBN, CBND, CBT discovered
1968	University of Mississippi	DEA grants UM permission to grow cannabis for research
1968	Werner Stober	Develops the Stober process for material science
1970	Controlled Substances Act	Signed by Nixon establishing the five drug schedules
1971	Paclitaxel	(Taxol) Isolated from the Yew tree. Used to treat many types of cancer
1972	Shafer Commission	Decriminalize marijuana possession. Ignored by White House
1978	Genentech	Synthesizes Human Insulin for production
1982	Humulin	Biosynthetic insulin is made commercially available by Eli Lilly.
1988	Allyn C. Howlett	Discovers the CB1, CB2 receptors and their function
1992	William Devane	Discovers the naturally occurring compound anandamide
1996	California	Legalizes cannabis for medical use
2000	Colorado	Legalizes cannabis for medical use
2001	Canada	Legalizes cannabis for medical use outlined in the Marihuana for Medical Purposes Regulations.
2003	U.S. Patent 6,630,507	Patent granted to the U.S. Government for Cannabis.
2003	Human Genome Project	Completed. (Note: project started in 1984)
2010	Nabiximol – (Sativex)	Cannabis extract approved in the United Kingdom
2014	Colorado	Legalizes cannabis for Adult Use
2016	California	Legalizes cannabis for Adult Use
2018	Right-to-Try	Allows pts. to try approved treatments for life-threatening diseases
2018	Ginko Bioworks	Strikes $125m deal to develop strains of cannabinoids – yeast
2018	Canopy Growth	Invests $429m to acquire IP for cannabis genetic breeding
2018	GW Pharma	Received FDA approval for Epidiolex (Note: EPIDIOLEX. $32,500 annual. Value doubled after + Trial Results)
2018	Canada	Legalizes cannabis for Adult use
2018	Hemp Farm Bill of 2018	Passed by the U.S. Congress
2019	Intrexon/Surterra	$122m deal to use yeast for production of cannabinoids
2019	Senators	Feinstein, Grassley, Schatz introduce bill to expand cannabis research
2019	Amyris	$300m deal with Lavvan to develop and synthesize cannabinoids
2019	Demetrix	Raises $50m to produce THC/CBD from yeast
2019	MORE ACT	Allows expungement of records avoiding future penalties
2019	EMA	Approves EPIDYOLEX
2019	SAFE ACT	Allows cannabis companies access to legal financial services
2019	U.S. Patent PP30,639 P2	Granted to CWB Holdings for Charlotte’s Web
2019	Prof. Raphael Mechoulam EPM	Introduce Synthetic Cannabinoid Acids.
2019	THCBD	Incorporated
2020	AXIM Biotech.	Clinical trials to start with synthetic dronabinol
2020	Professor Giuseppe Cannazza	University of Modena discovers THCP and CBDP
4900 BCE	click here	Cannabis Historical Timeline 2900 B.C.E to Present
Year	Subject	Discovery/Milestone